A REVIEW OF PKRRATING

autophosphorylation at T466 is not really feasible Within this geometry along with the docking web-site on helix αG with the substrate eIF2α is blocked. However, comparable interfaces employing the αEF and αG helices are already claimed for trans-autophosphorylation complexes of PAK159 and PknB60. The mechanistic relevance of activation loop e